The guide targets common failure modes, typical of many systems. However, real systems have their peculiarities, and part of their operation is irrelevant to most systems.
Real systems are complex and the design might be based on wrong assumption about its actual behavior, especially in exceptional situations.
35 years after the TMI incidence, it became evident that the operators had been trained to make a wrong diagnosis, which led to incorrect actions (source: https://atomicinsights.com/tmi-operators-took-actions-trained-take/) and that almost everyone associated with pressurized water reactor design and operation misunderstood how the system would respond to a leak in the steam space of the pressurizer. (sources: http://ansnuclearcafe.org/2014/08/05/correcting-history-can-be-an-uphill-battle/#sthash.doqX2wmZ.dpuf , http://ansnuclearcafe.org/2014/08/05/correcting-history-can-be-an-uphill-battle/#sthash.doqX2wmZ.dpbs ).
Beside employing the guidelines of this guide, you should always look for failure modes specific to your project, and find ways to handle them properly.
Updated on 01 Mar 2017.